ALIX anticorps

N° du produit ABIN181090

Cet anticorps Souris Monoclonal détecte spécifiquement ALIX dans WB, IF, IP, IHC (p) et EIA. Il présente une réactivité envers Humain, Souris, Rat et Xenopus laevis.

Aperçu rapide pour ALIX anticorps (ABIN181090)

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Reactivité: Humain, Souris, Rat, Xenopus laevis

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ALIX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3A9

Détail du produit anti-ALIX anticorps

Specificité: This antibody recognises apoptotic-linked-gene-product 2 (ALG-2) interacting protein X (ALIX), a conserved adaptor protein which is ubiquitously expressed.

Attributs du produit: Synonyms: PDCD6-interacting protein, ALG-2-interacting protein 1, Hp95, KIAA1375, Programmed celldeath 6-interacting protein

Purification: Affinity Chromatography on Protein G

Immunogène: Alix fusion protein.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Paraffin Sections: This product does not require proteindigestion pre-treatment of paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ALIX

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Autre désignation: ALIX / PDCD6IP

Sujet: ALIX was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly. ALG2 interacting protein X is a Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen. In case of infection, the HIV-1 virus directly takes advantage of its function for viral exocytosis and budding, via its interaction with HIV-1 p6 protein. It may play a role in the regulation of both apoptosis and cell proliferationSynonyms: ALG-2-interacting protein 1, Hp95, KIAA1375, PDCD6-interacting protein, Programmed cell death 6-interacting protein

ID gène: 10015

UniProt: Q8WUM4

Pathways: Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation